Drugs & Vitamins

Active Ingredients: Letrozole
Other Names: Femara
Drug Class: Aromatase Inhibitor
Rx Status: Available by prescription only
Generic Available: No
Product Images & Descriptions:

What is/are Letrozole? (Back to top)
LETROZOLE blocks the production of estrogen. Certain types of breast cancer grow under the influence of estrogen. Letrozole helps block tumor growth. This medicine is used to treat advanced breast cancer in postmenopausal women. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care providers before I take this medicine? (Back to top)
They need to know if you have any of these conditions:

• liver disease
• osteoporosis (weak bones)
• an unusual or allergic reaction to letrozole, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine? (Back to top)
Take this medicine by mouth with a glass of water. You may take it with or without food. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose? (Back to top)
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine? (Back to top)
Do not take this medicine with any of the following:

• estrogens, like hormone replacement therapy or birth control pills

• dietary supplements such as androstenedione or DHEA
• prasterone
• tamoxifen

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What side effects may I notice from this medicine? (Back to top)
Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching, or hives
• bone fracture
• chest pain
• difficulty breathing or shortness of breath
• severe pain, swelling, warmth in the leg
• unusually weak or tired
• vaginal bleeding

• bone, back, joint, or muscle pain
• dizziness
• fatigue
• fluid retention
• headache
• hot flashes, night sweats
• nausea
• weight gain

This list may not describe all possible side effects.

What should I watch for while using this medicine? (Back to top)
Visit your doctor or health care professional for regular check-ups to monitor your condition.

Do not use this drug if you are pregnant. Serious side effects to an unborn child are possible. Talk to your doctor or pharmacist for more information.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

Where should I keep this medicine? (Back to top)
Keep out of the reach of children.

Store between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Last Updated:May 31, 2006

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